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As of 2026-08-24, Karyopharm Therapeutics Inc. (KPTI) has a 3-month relative strength percentile of 2 within the TickerStance CS+ADRC universe (~5,000 tickers). Its Power rating (absolute 1–99) is 25. The current market Stance is 47.8 (Neutral). Sector: Healthcare, ranked 3 of 11. Average daily range 10.4%, relative volume 0.33×. TickerStance reports observed regime conditions across the full CS+ADRC universe; band assignment reflects current breadth, momentum, and macro inputs computed at the daily close. Percentile ranks run from 1 (weakest) to 99 (strongest) relative to all universe members on the same date.
KPTI is in a stage 3 topping pattern, week 2. Extended from base. VCP detected: inconclusive. Distance from 50d / 200d: -71.9% / -74.5%.
Relative strength across horizons plus the leadership score.
Accumulation rating, relative volume, U/D ratio, breakout-day proof.
Diluted EPS, last 8 quarters. Loss makers are judged by progress toward breakeven.
KPTI appears in 1 ETF as of Apr 2026: PRFZ at 0.00% weight, $139K notional.
Held by 5 ETFs · $4M across latest filings · largest weight 0.12% (TMED).
Top 1 by value, from SEC N-PORT-P filings dated Apr 2026.
| ETF | Weight | Value | Δ |
|---|---|---|---|
| PRFZ | 0.00% | $139K | — |
As filed in N-PORT — quarterly holdings with up to ~60-day publication lag. Not live positioning.
Weak relative strength and quiet attention. Little to read here either way.
Measures how unusual this name’s public attention is against its own 90-day history — a surprise reading, not a ranking of how watched it is versus other stocks. Intel, not a signal.
Daily range, ATR, beta, and the math for a 1-ADR stop.
YoY sales growth, last 8 quarters. Sales must back the earnings story.
TTM operating margin. Expansion = real operating leverage.
YoY common shares outstanding. Down = buyback tailwind. Up > 2% = dilution flag.
Reported figures from SEC filings. No analyst estimates or forward guidance.
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| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | KPTI Jan avg: -8.90% median: -9.71% win: 0% σ: 4.52% n: 4 2022-04-12 → 2026-07-31 | KPTI Feb avg: 18.90% median: 17.92% win: 50% σ: 35.61% n: 4 2022-04-12 → 2026-07-31 | KPTI Mar avg: -8.70% median: -6.00% win: 50% σ: 44.38% n: 4 2022-04-12 → 2026-07-31 | KPTI Apr avg: 13.83% median: -7.97% win: 40% σ: 48.60% n: 5 2022-04-12 → 2026-07-31 | KPTI May avg: -13.62% median: -5.91% win: 40% σ: 22.32% n: 5 2022-04-12 → 2026-07-31 | KPTI Jun avg: -9.89% median: -10.47% win: 40% σ: 15.07% n: 5 2022-04-12 → 2026-07-31 | KPTI Jul avg: -16.64% median: -5.76% win: 40% σ: 36.86% n: 5 2022-04-12 → 2026-07-31 | KPTI Aug avg: 13.42% median: -2.03% win: 50% σ: 53.27% n: 4 2022-04-12 → 2026-07-31 (current) | KPTI Sep avg: 3.44% median: 6.30% win: 75% σ: 7.87% n: 4 2022-04-12 → 2026-07-31 | KPTI Oct avg: -9.99% median: -12.07% win: 25% σ: 22.32% n: 4 2022-04-12 → 2026-07-31 | KPTI Nov avg: -4.52% median: -7.30% win: 25% σ: 11.51% n: 4 2022-04-12 → 2026-07-31 | KPTI Dec avg: -3.10% median: -3.82% win: 50% σ: 30.26% n: 4 2022-04-12 → 2026-07-31 |