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As of 2026-08-24, Upstream Bio, Inc. Common Stock (UPB) has a 3-month relative strength percentile of 19 within the TickerStance CS+ADRC universe (~5,000 tickers). Its Power rating (absolute 1–99) is 36. The current market Stance is 47.8 (Neutral). Sector: Healthcare, ranked 3 of 11. Average daily range 6.6%, relative volume 0.87×. TickerStance reports observed regime conditions across the full CS+ADRC universe; band assignment reflects current breadth, momentum, and macro inputs computed at the daily close. Percentile ranks run from 1 (weakest) to 99 (strongest) relative to all universe members on the same date.
UPB is in a stage 4 downtrend, week 1. Extended from base. VCP detected: inconclusive. Distance from 50d / 200d: -3.5% / -55.0%.
Relative strength across horizons plus the leadership score.
Accumulation rating, relative volume, U/D ratio, breakout-day proof.
Daily range, ATR, beta, and the math for a 1-ADR stop.
Diluted EPS, last 8 quarters. Loss makers are judged by progress toward breakeven.
YoY sales growth, last 8 quarters. Sales must back the earnings story.
Operating margin unavailable
YoY common shares outstanding. Down = buyback tailwind. Up > 2% = dilution flag.
Reported figures from SEC filings. No analyst estimates or forward guidance.
UPB is held by 19 ETFs as of May 2026. Top owner: VTWO at 0.01% weight, $1M notional. Top 3 carry $3M.
Held by 37 ETFs · $43M across latest filings · largest weight 1.01% (SURI).
Top 10 by value, from SEC N-PORT-P filings dated May 2026.
| ETF | Weight | Value | Δ |
|---|---|---|---|
| VTWO | 0.01% | $1M | — |
| SCHASchwab U.S. Small-Cap ETF | 0.01% | $1M | — |
| VHTVanguard Health Care ETF | 0.00% | $606K | — |
| AVSC | 0.02% | $523K | — |
| SBIO | 0.29% | $466K | +0.02 pp |
| VTWV | 0.02% | $212K | — |
| FMED | 0.51% | $208K | +0.31 pp |
| SCHBSchwab U.S. Broad Market ETF | 0.00% | $171K | — |
| IBBQ | 0.04% | $24K | — |
| VTHRVanguard Russell 3000 ETF | 0.00% | $21K | — |
Showing 10 of 19 ETF owners.
As filed in N-PORT — quarterly holdings with up to ~60-day publication lag. Not live positioning.
Weak relative strength and quiet attention. Little to read here either way.
Measures how unusual this name’s public attention is against its own 90-day history — a surprise reading, not a ranking of how watched it is versus other stocks. Intel, not a signal.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | UPB Jan avg: -10.01% median: -10.01% win: 50% σ: 34.62% n: 2 2024-10-14 → 2026-07-31 | UPB Feb avg: -50.83% median: -50.83% win: 0% σ: 34.59% n: 2 2024-10-14 → 2026-07-31 | UPB Mar avg: -2.82% median: -2.82% win: 50% σ: 28.29% n: 2 2024-10-14 → 2026-07-31 | UPB Apr avg: 26.65% median: 26.65% win: 100% σ: 34.87% n: 2 2024-10-14 → 2026-07-31 | UPB May avg: -4.63% median: -4.63% win: 0% σ: 6.09% n: 2 2024-10-14 → 2026-07-31 | UPB Jun avg: 0.87% median: 0.87% win: 50% σ: 25.59% n: 2 2024-10-14 → 2026-07-31 | UPB Jul avg: 15.31% median: 15.31% win: 50% σ: 34.12% n: 2 2024-10-14 → 2026-07-31 | UPB Aug avg: 11.89% median: 11.89% win: 100% σ: 0.00% n: 1 2024-10-14 → 2026-07-31 (current) | UPB Sep avg: 9.81% median: 9.81% win: 100% σ: 0.00% n: 1 2024-10-14 → 2026-07-31 | UPB Oct avg: 25.08% median: 25.08% win: 100% σ: 17.46% n: 2 2024-10-14 → 2026-07-31 | UPB Nov avg: -0.59% median: -0.59% win: 50% σ: 15.88% n: 2 2024-10-14 → 2026-07-31 | UPB Dec avg: -14.95% median: -14.95% win: 0% σ: 13.97% n: 2 2024-10-14 → 2026-07-31 |